Opexa Therapeutics Inc. (Nasdaq: OPXA) shares leaped 80.8 percent to $2.82. Volume of 3.2 million shares, triumphed over usual volume of 70,317. The Woodlands, Texas-based cell therapy company said that after meeting twice with the U.S. Food and Drug Administration, it is preparing a Phase III clinical study of Tovaxin, a drug intended to treat multiple sclerosis.
Citigroup (NYSE:C) was a volume leader Wednesday, trading in 122,929,357, gaining on a full-day average of 538,020,000. Shares gained 0.7 percent to $4.94.
Tasty Baking Company (Nasdaq: TSTY) shed 33 percent to $4.31, on 159,504, compared to usual volume of below 10,000. TSTY announced today that preliminary financial data indicate the Company did not achieve the expected operational cash savings from this bakery during the fourth quarter.