Arena Pharmaceuticals, Inc. (ARNA) – Buzz Stock of the Day

Posted on Thursday, July 1st, 2010

Shares of drug maker Arena Pharmaceuticals, Inc. (Nasdaq: ARNA) surged 20 percent from Wednesday’s close, in morning trading on Thursday after it was announced that Japanese drug maker, Eisai, Inc. will market Arena’s obesity treatment lorcaserin in the U.S.

“Execution of this commercial agreement is a major milestone in our plans for lorcaserin,” said Jack Lief, Arena’s President and Chief Executive Officer. “We believe in Eisai’s human health care mission to satisfy unmet medical needs and increase benefits to patients and their families.”

Here are a few highlights from the deal:

  • $50 million initial upfront (kind of small when considering the potential of the drug)
  • $90 million upon FDA Approval (PDUFA October 22nd) bringing upfront for US marketing rights to $140 million
  • $1.16B in one-time purchase price adjustments after certain sales goals.
  • 31.5-36.5% of annual Lorcaserin sales
  • [–quote–]
    The U.S. Food and Drug Administration is already reviewing lorcaserin, and an decision is expected on Oct. 22. The main concern with lorcaserin is that patients treated with the drug in two pivotal phase III studies didn’t lose much weight — a little more than 3% on a placebo adjusted basis. The biggest plus in lorcaserin’s corner is the drug’s safety and tolerability, which appear better than competing drugs.

    “With Eisai, we have the right company to market lorcaserin in the United States, the right type of agreement to optimize lorcaserin’s medical and commercial potential and the shared recognition that it is the right time to enter into this agreement to prepare for launch following FDA approval,” Lief said.

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