Gentium SpA (Nasdaq: GENT) rocketed up 14.1 percent to $8.99 Wednesday afternoon. Volume of 154,050 shares proved four times its full-day average. Italian-based GENT is a biopharmaceutical company focused on the development and manufacture of drugs to treat and prevent a variety of diseases and conditions.

Ford Motor Company (NYSE: F) was among the top traders Wednesday, dealing in 59,850,360 shares, making headway on its full-day average of 83,462,800. Prices for F fell 4.5 percent, though, to $17.86.

China Shen Zhou Mining and Resources (AMEX: SHZ) settled in price 18.3 percent Wednesday to $6.63. Volume was 5,817,660 shares, surpassed its aevrage daily volume of 3,876,320. Wednesday, SHZ announced that it has entered into a securities purchase agreement with several institutional investors for a registered direct placement of approximately $20 million of common stock at a price of $7.05 per share.