WSB Holdings Inc. (NasdaqGM: WSB) gained 19.06 percent in price Wednesday to close at $2.77. Volume of 9,977 shares more than tripled its daily average. Headquartered in the Baltimore-Washington corridor, WSB serves the banking needs of growing businesses with commercial lending facilities, commercial real estate financing, residential mortgages, and residential construction financing for both developers and individual home owners.

Human Genome Sciences Inc. (NasdaqGM: HGSI) was active in Wednesday trading, with volume of 32,900,723, more than 10 times its usual daily volume. HGSI shares faded, however, 5.29 percent in price to $24.51. Tuesday, HGSI and GlaxoSmithKline PLC (GSK) announced that the Arthritis Advisory Committee of the U.S. Food and Drug Administration (FDA) has voted 13 to 2 to recommend that the FDA approve BENLYSTA® (belimumab) for the treatment of autoantibody-positive patients with active systemic lupus erythematosus (SLE).

GT Solar International Inc. (NasdaqGS: SOLR) fell in price Wednesday by 15.38 percent to close at $7.10. Its volume of 10,123,799 shares towered over its three-month daily average of 3,485,580. SOLR is a global provider of polysilicon production technology, and sapphire and silicon crystalline growth systems and materials for the solar, LED and other specialty markets