Posts Tagged ‘PRAN’

Prana Biotechnology Ltd. (PRAN) soars on news of effectiveness of Alzheimer’s treatment

Monday, September 19th, 2011

Shares of Prana Biotechnology Ltd. (Nasdaq: PRAN) touched a daily high of $2.31 per share, up more than 34 percent from Friday’s closing price, after it was announced that The Journal Of Neurochemistry has published an update on the mechanism of action of PBT2 in the treatment of Alzheimer’s Disease.

The study explains how PBT2 is able to restore cognition in AD sufferers through repair of affected Alzheimer’s brains. The findings further explain the rapid improvement in cognition previously reported in transgenic Alzheimer’s mice and in patients in a Phase IIa clinical trial with PBT2. These new results further explain how PBT2 can achieve rapid improvements in cognition: by liberation of copper and zinc trapped in amyloid deposits and returning those essential metals to neurons, where they are needed for normal function.

The Australia-based Prana Biotechnology Ltd. also recently received a “very positive reaction” from international patient groups and researchers at this week’s World Congress on Huntington’s Disease in Melbourne, according to a September 15 press release.

Huntington’s disease is a disorder passed down through families in which nerve cells in certain parts of the brain waste away, or degenerate.

“Prana and our collaborators at major research institutions have been conducting extensive research into neurodegenerative diseases for more than a decade, including our efforts to learn more about Huntington’s,” said Prana’s Executive Chairman, Geoffrey Kempler in the September 15 press release. “Since we decided to conduct a Phase IIa trial of our experimental drug PBT2 in Huntington’s patients, the Huntington’s community has been very quick to support our research program.”

Prana Biotechnology Ltd. engages in the research and development of therapeutic drugs for neurological diseases in Australia. The company primarily focuses on the Alzheimer‘s, Parkinson‘s, and Huntington‘s diseases, as well as various age-related degenerative disorders. Its development stage product line includes PBT2, a phase IIb clinical product intended for the Alzheimer’s disease; and PBT2, a phase IIa clinical product for the Huntington’s disease.

PRAN makes hay, SIRI sells, KNDI hobbled

Thursday, March 31st, 2011

Prana Biotechnology (NASDAQ : PRAN) vaulted 7.6% to $2.83, on volume of 2.5 million or 2 ½ times its daily average. This, after announcing that the Alzheimer’s Drug Discovery Foundation will provide Prana with a mission-related investment of $700,000 over two years to conduct a clinical trial investigating the potential of PBT2 to reduce the accumulation of beta-amyloid in the brain of people with Alzheimer’s Disease.

Sirius XM Radio Inc. (Nasdaq: SIRI) beamed out 43.6 million shares Thursday, catching up on its daily average of 52.6 million. Prices subsided, though, 4.1%, to $1.64, amid word that its antitrust lawsuit has been approved for class-action status.

Kandi Technologies, Corp. (NASDAQ: KNDI) shares dipped 12.5% to $2.95. Volume for KNDI was 367,558, closing the gap with its daily average of around 380,000, after it reported 2010 revenues increased 26.8% to $42.9 million. On a non-GAAP basis, which excludes certain warrants, options and convertible notes related charges, the Company reported 2010 adjusted net income of $5.0 million, up 76% from the prior year.